Type 2 diabetes is a progressive condition in which the body becomes resistant to the normal effects of insulin and/or gradually loses the capacity to produce enough insulin in the pancreas. We do not know what causes type 2 diabetes. Type 2 diabetes is associated with modifiable lifestyle risk factors. Type 2 diabetes also has strong genetic and family related risk factors.
Type 2 Diabetes:
What happens with Type 2 diabetes?
Type 2 diabetes develops over a long period of time (years). During this period of time insulin resistance starts, this is where the insulin is increasingly ineffective at managing the blood glucose levels. As a result of this insulin resistance, the pancreas responds by producing greater and greater amounts of insulin, to try and achieve some degree of management of the blood glucose levels.
As insulin overproduction occurs over a very long period of time, the insulin producing cells in the pancreas wear themselves out, so that by the time someone is diagnosed with type 2 diabetes, they have lost 50 – 70% of their insulin producing cells. This means type 2 diabetes is a combination of ineffective insulin and not enough insulin. When people refer to type 2 diabetes as a progressive condition they are referring to the ongoing destruction of insulin producing cells in the pancreas.
Initially, type 2 diabetes can often be managed with healthy eating and regular physical activity. Over time most people with type 2 diabetes will also need tablets and many will eventually require insulin. It is important to note that this is the natural progression of the condition, and taking tablets or insulin as soon as they are required can result in fewer long-term complications.
What causes Type 2 diabetes?
Diabetes runs in the family. If you have a family member with diabetes, you have a genetic disposition to the condition.
While people may have a strong genetic disposition towards type 2 diabetes, the risk is greatly increased if people display a number of modifiable lifestyle factors including high blood pressure, overweight or obesity, insufficient physical activity, poor diet and the classic ‘apple shape’ body where extra weight is carried around the waist.
People are at a higher risk of getting Type 2 diabetes if they:
Check your risk – answer 10 short questions on the diabetes risk calculator.
Read our section on preventing type 2 diabetes.
Symptoms
Many people with type 2 diabetes display no symptoms. As type 2 diabetes is commonly (but not always) diagnosed at a later age, sometimes signs are dismissed as a part of ‘getting older’. In some cases, by the time type 2 diabetes is diagnosed, the complications of diabetes may already be present.
Symptoms include: